P2Y Receptor
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P2Y Receptor Inhibitors
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P2Y Receptor Ligands
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P2Y Receptor Related Products (121)
Related Products (121)
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P1,P2-Diuridine-5’-diphosphate
0 ImagesCat. No.: HY-137602CAS No.: 26184-65-6Synonyms: Up2UP1,P2-Diuridine-5’-diphosphate (Up2U) is a symmetrical dinucleoside polyphosphate containing two pyrimidine base moieties. P1,P2-Diuridine-5’-diphosphate is also an activator of purinergic P2Y receptor.
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Cangrelor tetrasodium (Standard)
0 ImagesSynonyms: AR-C69931MX tetrasodium (Standard)Cangrelor (tetrasodium) (Standard) is the analytical standard of Cangrelor (tetrasodium). This product is intended for research and analytical applications. Cangrelor tetrasodium, an adenosine triphosphate analogue, is a reversible and selective platelet P2Y12 antagonist, with prompt and potent antiplatelet effects. Cangrelor tetrasodium directly blocks adenosine diphosphate (ADP)-induced activation and aggregation of platelets. Cangrelor tetrasodium is also a nonspecific GPR17 antagonist.
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(±)-Clopidogrel-d7 sulfate
0 ImagesCat. No.: HY-15283ASCAS No.: 1346598-07-9Synonyms: (±)-Clopidogrelum-d7 sulfate(±)-Clopidogrel-d7 (sulfate) is the deuterium labeled (±)-Clopidogrel sulfate.
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2-MeS-ATP
0 ImagesCat. No.: HY-137418CAS No.: 43170-89-4Synonyms: 2-Methylthio-ATP2-MeS-ATP (2-Methylthio-ATP) is an analog of adenosine nucleotides and acts as a P2Y purinergic receptor agonist specific for adenosine nucleotide activation. 2-MeS-ATP is also able to inhibit the release of toxic mediators from macrophages stimulated by endotoxin (LPS). 2-MeS-ATP can be used in the study of endotoxin shock and inflammatory diseases.
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Chloramphenicol succinate sodium (Standard)
0 ImagesCat. No.: HY-N7114ARCAS No.: 982-57-0Chloramphenicol succinate sodium (Standard) is the analytical standard of Chloramphenicol succinate sodium. This product is intended for research and analytical applications. Chloramphenicol succinate sodium is a prodrug of Chloramphenicol (HY-B0239), acting as a P2Y14R inhibitor with an IC50 of 1.585 nM. Chloramphenicol succinate sodium serves as a competitive substrate and inhibitor of succinate dehydrogenase (SDH), which may account for its toxicity. Chloramphenicol succinate sodium exerts a significant inhibitory effect on colitis. Chloramphenicol succinate sodium can be used in research related to myelosuppression, gray baby syndrome, aplastic anemia, bacterial meningitis and inflammatory bowel disease.
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Uridine-5'-diphosphate disodium salt (Standard)
0 ImagesSynonyms: UDP disodium salt (Standard)Uridine-5'-diphosphate (UDP) disodium salt (Standard) is the analytical standard of Uridine-5'-diphosphate disodium salt (HY-W010832). This product is intended for research and analytical applications. Uridine-5'-diphosphate disodium salt is an important nucleotide made of uracil, ribose, and a pyrophosphate group. Uridine-5'-diphosphate disodium salt is a potent, selective human P2Y6 receptor native agonist (EC50 = 300 nM; pEC50 = 6.52). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis.
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Prasugrel hydrochloride (Standard)
0 ImagesCat. No.: HY-15284ARCAS No.: 389574-19-0Synonyms: PCR 4099 hydrochloride (Standard)Prasugrel (hydrochloride) (Standard) is the analytical standard of Prasugrel (hydrochloride). This product is intended for research and analytical applications. Prasugrel hydrochloride (PCR 4099 hydrochloride), a thienopyridine and proagent, inhibits platelet function. Prasugrel hydrochloride is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation.
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ATPγS tetralithium salt (Standard)
0 ImagesCat. No.: HY-108666RCAS No.: 93839-89-5Synonyms: Adenosine-5'-O-(3-thiotriphosphate) tetralithium salt (Standard); Adenosine 5'-[γ-thio]triphosphate tetralithium salt (Standard)ATPγS tetralithium salt (Standard) is the analytical standard of ATPγS (tetralithium salt) (HY-108666). This product is intended for research and analytical applications. ATPγS (tetralithium salt) is a P2Y11 receptor agonist, an antioxidant and a neuroprotective agent. ATPγS (tetralithium salt) can be used as a substrate for the nucleotide hydrolysis and RNA unwinding activities of eukaryotic translation initiation factor eIF4A. ATPγS (tetralithium salt) is active in ATP hydrolysis.
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5'-UMPS
0 ImagesCat. No.: HY-131822CAS No.: 15548-52-4Synonyms: Uridine-5'-O-monophosphorothioate5'-UMPS (Uridine-5'-O-monophosphorothioate) is a P2Y14 receptor agonist. 5'-UMPS can induce HeLa cell growth slightly.
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PSB-0739 (Standard)
0 ImagesCat. No.: HY-108660RCAS No.: 1052087-90-7PSB-0739 (Standard) is the analytical standard of PSB-0739 (HY-108660). This product is intended for research and analytical applications. PSB-0739 is a high-affinity potent, competitive, nonselective platelet P2Y12 receptor antagonist with a Ki values of 24.9 nM. The P2Y12 receptor plays a crucial role in platelet aggregation. Antithrombotic effect.
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BX 667
0 ImagesCat. No.: HY-111064CAS No.: 937395-08-9BX 667 is an orally active reversible P2Y(12) receptor antagonist. BX 667 attenuates thrombosis.
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Sp-ATPαS
0 ImagesCat. No.: HY-137626CAS No.: 58976-48-0Sp-ATPαS is a regulator of ATP-binding proteins. Sp-ATPαS is a competitive antagonist of the human P2Y1 receptor, which can inhibit the calcium signal induced by ADP. Sp-ATPαS is metabolically more stable than ATP. Sp-ATPαS can be used to study the binding patterns of metals and nucleotides in enzymatic reactions.
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MRS2298
0 ImagesCat. No.: HY-113723CAS No.: 491611-43-9MRS2298? is a potent acyclic P2Y1 receptor antagonist with a Ki of 29.6 nM. MRS2298 inhibits the ADP-induced aggregation of human platelets with an IC50 of 62.8 nM. MRS2298 inhibits Ca2+ rise in platelets with an IC50 of 810 nM.
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PPTN (Standard)
0 ImagesCat. No.: HY-110322ARCAS No.: 1160271-30-6PPTN (Standard) is the analytical standard of PPTN (HY-110322A). This product is intended for research and analytical applications. PPTN, a chemical probe, is a potent, high-affinity, competitive and highly selective P2Y14 receptor antagonist with a KB value of 434 pM. PPTN exhibits no agonist or antagonist effect at the P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors. Anti-inflammatory and immune activity.
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PIT (Standard)
0 ImagesCat. No.: HY-108662RCAS No.: 56583-49-4Synonyms: 2,2'-Pyridylisatogen tosylate (Standard)PIT (Standard) is the analytical standard of PIT (HY-108662). This product is intended for research and analytical applications. PIT (2,2'-Pyridylisatogen tosylate) is a selective and non-competitive antagonist of P2Y1 receptor with an IC50 value of 0.14 μM for human P2Y1 receptor. PIT antagonizes P2Y1 receptor signaling without affecting nucleotide binding. PIT is an irreversible antagonist of responses to ATP at metabotropic purinoceptors (of the P2Y family) in some smooth muscles. PIT can be used for the research of chronic bronchitis and asthma.
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Selatogrel (Standard)
0 ImagesCat. No.: HY-109122RCAS No.: 1159500-34-1Synonyms: ACT-246475 (Standard)Selatogrel (Standard) is the analytical standard of Selatogrel (HY-109122). This product is intended for research and analytical applications. Selatogrel (ACT-246475) is a reversible and selective P2Y12 receptor antagonist which inhibits platelet aggregation with an IC50 of 8 nM. Selatogrel exhibits antithrombotic efficacy.
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S-Geranylgeranyl-L-glutathione
0 ImagesCat. No.: HY-158813CAS No.: 2364639-42-7S-Geranylgeranyl-L-glutathione is a P2RY8 inhibitor and intercellular signaling molecule that exists endogenously in human bone marrow interstitial fluid. S-Geranylgeranyl-L-glutathione promotes the internalization of P2RY8 and antagonizes chemokine-induced activation of pAkt. S-Geranylgeranyl-L-glutathione negatively regulates the migration of B cells and T cells to the bone marrow, inhibits chemokine-mediated migration of germinal center B cells and follicular helper T cells, participates in lymphocyte guidance regulation, and modulates the germinal center response process. S-Geranylgeranyl-L-glutathione can be used in research related to diffuse large B-cell lymphoma and Burkitt lymphoma.
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MRS 2578 (Standard)
0 ImagesCat. No.: HY-13104RCAS No.: 711019-86-2MRS 2578 (Standard) is the analytical standard of MRS 2578. This product is intended for research and analytical applications. MRS 2578 is a selective and potent P2Y6 receptor antagonist with IC50s of 37 nM (human) and 98 nM (rat). MRS 2578 exhibits insignificant activity at P2Y1, P2Y2, P2Y4, and P2Y11 receptors.
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Acid blue 129
0 ImagesCat. No.: HY-W412336CAS No.: 6397-02-0Acid blue 129 is an acidic dye and highly selective antagonist at the P2Y-receptor of the guinea pig taenia coli. Acid blue 129 does not show any effect at the P2X-receptor of the rat vas deferens. Acid blue 129 can be used for the dyeing of cotton, wool, silk, nylon, paper and leather.
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5'-TMPS
0 ImagesCat. No.: HY-131821CAS No.: 15548-51-3Synonyms: Thymidine-5'-O-monophosphorothioate5'-TMPS (Thymidine-5'-O-monophosphorothioate) is a selective partial agonist of P2Y6R and an antagonist of P2Y14R. Additionally, 5'-TMPS acts as a positive regulator of angiogenesis, exhibiting pro-angiogenic effects
